The Indigenous community of Maskwacis, Alberta is grappling with the devastating impact of the opioid crisis, with 83 deaths reported since 2020. Efforts are being made to combat the crisis, including a mobile treatment unit and naloxone training. The community has also launched an opioid class action against pharmaceutical companies. The crisis is closely linked with issues of homelessness and crime, making it a complex issue to address. However, the community’s resilience and determination to find solutions provide hope amidst the crisis.